3DVU
Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and the Beclin 1 BH3 domain
Summary for 3DVU
Entry DOI | 10.2210/pdb3dvu/pdb |
Related | 3BL2 |
Descriptor | V-bcl-2, Beclin-1 (3 entities in total) |
Functional Keywords | autophagy, protein-protein complex, viral bcl-2, beclin 1, apoptosis, m11, antiviral defense, bh3 domain, coiled coil, cytoplasm, golgi apparatus, membrane, polymorphism, viral protein-apoptosis complex, viral protein/apoptosis |
Biological source | Murid herpesvirus 4 (MuHV-4) More |
Total number of polymer chains | 4 |
Total formula weight | 38996.15 |
Authors | Sinha, S. (deposition date: 2008-07-20, release date: 2008-10-07, Last modification date: 2023-11-01) |
Primary citation | Sinha, S.,Colbert, C.L.,Becker, N.,Wei, Y.,Levine, B. Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11. Autophagy, 4:989-997, 2008 Cited by PubMed: 18797192DOI: 10.4161/auto.6803 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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