3DTX

Crystal structure of HLA-B*2705 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)

3DTX の概要

• エントリーDOI: 10.2210/pdb3dtx/pdb
• 関連するPDBエントリー: 1OF2 1OGT 3B3I 3B6S
• 分子名称: MHC class I antigen (Fragment), Beta-2-microglobulin, Double citrullinated vasoactive intestinal polypeptide receptor, ... (4 entities in total)
• 機能のキーワード: immune system-complex, mhc (major histocompatibility complex) i, hla-b*2705, glycoprotein, host-virus, immune response, immunoglobulin domain, host-virus interaction, membrane, transmembrane, disease mutation, glycation, secreted, mhc i, pyrrolidone carboxylic acid, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: A3F718; Secreted: P61769
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45207.16

構造登録者

Beltrami, A.,Gabdulkhakov, A.,Rossmann, M.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W. (登録日: 2008-07-16, 公開日: 2009-05-05, 最終更新日: 2023-12-27)

• 主引用文献: Beltrami, A.,Gabdulkhakov, A.,Rossmann, M.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W.; Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide; To be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)