3B3I

Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes

Summary for 3B3I

Entry DOI	10.2210/pdb3b3i/pdb
Related	1OF2 1OGT
Descriptor	HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, Vasoactive intestinal polypeptide receptor 1, ... (5 entities in total)
Functional Keywords	hla-b2709, ankylosing spondylitis, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, g-protein coupled receptor, phosphorylation, receptor, transducer, protein binding, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P03989 Secreted . Note=(Microbial infection) In the presence of M: P61769 Cell membrane; Multi-pass membrane protein: P32241
Total number of polymer chains	3
Total formula weight	45782.81
Authors	Beltrami, A.,Rossmann, M.,Fiorillo, M.T.,Paladini, F.,Sorrentino, R.,Saenger, W.,Kumar, P.,Ziegler, A.,Uchanska-Ziegler, B. (deposition date: 2007-10-22, release date: 2008-07-22, Last modification date: 2023-11-15)
Primary citation	Beltrami, A.,Rossmann, M.,Fiorillo, M.T.,Paladini, F.,Sorrentino, R.,Saenger, W.,Kumar, P.,Ziegler, A.,Uchanska-Ziegler, B. Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes. J.Biol.Chem., 283:27189-27199, 2008 Cited by PubMed: 18650441 DOI: 10.1074/jbc.M802818200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation