3DR4

GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand

3DR4 の概要

• エントリーDOI: 10.2210/pdb3dr4/pdb
• 関連するPDBエントリー: 3bn1 3dr7
• 分子名称: Putative perosamine synthetase, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: perosamine, deoxysugar, pyridoxal phosphate, aspartate aminotransferase, o-antigen, transferase
• 由来する生物種: Caulobacter crescentus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 175326.01

構造登録者

Holden, H.M.,Cook, P.D.,Carney, A.E. (登録日: 2008-07-10, 公開日: 2008-10-14, 最終更新日: 2023-08-30)

• 主引用文献: Cook, P.D.,Carney, A.E.,Holden, H.M.; Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase; Biochemistry, 47:10685-10693, 2008; PubMed: 18795799; DOI: 10.1021/bi801309q

実験手法

X-RAY DIFFRACTION (1.6 Å)