3DPR

Human rhinovirus 2 bound to a concatamer of the VLDL receptor module V3

3DPR の概要

• エントリーDOI: 10.2210/pdb3dpr/pdb
• 分子名称: Protein VP1, Protein VP2, Protein VP3, ... (7 entities in total)
• 機能のキーワード: human rhinovirus, vldl-receptor, virus-protein complex, icosahedral virus, atp-binding, capsid protein, covalent protein-rna linkage, cytoplasmic vesicle, helicase, host-virus interaction, hydrolase, lipoprotein, membrane, myristate, nucleotide-binding, nucleotidyltransferase, phosphoprotein, protease, rna replication, rna-binding, rna-directed rna polymerase, thiol protease, transferase, virion, cholesterol metabolism, coated pit, egf-like domain, endocytosis, glycoprotein, lipid metabolism, lipid transport, receptor, steroid metabolism, transmembrane, transport, vldl, virus
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P04936 P04936 P04936 P04936; Membrane; Single-pass type I membrane protein: P98155
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 99914.08

構造登録者

Querol-Audi, J.,Pous, J.,Fita, I.,Verdaguer, N. (登録日: 2008-07-09, 公開日: 2009-04-07, 最終更新日: 2017-10-25)

• 主引用文献: Querol-Audi, J.,Konecsni, T.,Pous, J.,Carugo, O.,Fita, I.,Verdaguer, N.,Blaas, D.; Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition; Febs Lett., 583:235-240, 2009; PubMed: 19073182; DOI: 10.1016/j.febslet.2008.12.014

実験手法

X-RAY DIFFRACTION (3.5 Å)