3DPP

Crystal structure of the substrate binding domain of E. coli DnaK in complex with a long pyrrhocoricin-derived inhibitor peptide (form A)

3DPP の概要

• エントリーDOI: 10.2210/pdb3dpp/pdb
• 関連するPDBエントリー: 3DPO 3DPQ
• 分子名称: Chaperone protein dnaK, inhibitor peptide, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: molecular chaperone, dnak, hsp70, substrate-binding domain, pyrrhocoricin inhibitor, atp-binding, chaperone, cytoplasm, dna replication, membrane, nucleotide-binding, phosphoprotein, stress response, peptide binding protein
• 由来する生物種: Escherichia coli; 詳細
• 細胞内の位置: Cytoplasm : P0A6Y8
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 52671.46

構造登録者

Roujeinikova, A. (登録日: 2008-07-09, 公開日: 2009-03-10, 最終更新日: 2023-08-30)

• 主引用文献: Liebscher, M.,Roujeinikova, A.; Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.; J.Bacteriol., 191:1456-1462, 2009; PubMed: 19103929; DOI: 10.1128/JB.01131-08

実験手法

X-RAY DIFFRACTION (2.5 Å)