3DP9

Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin A

3DP9 の概要

• エントリーDOI: 10.2210/pdb3dp9/pdb
• 分子名称: MTA/SAH nucleosidase, (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, IODIDE ION, ... (4 entities in total)
• 機能のキーワード: vibrio cholerae 5'-methylthioadenosine/s-adenosyl homocysteine nucleosidase, butylthio dadme immucillin a, mtan, hydrolase
• 由来する生物種: Vibrio cholerae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49888.07

構造登録者

Ho, M.,Gutierrez, J.A.,Crowder, T.,Rinaldo-Matthis, A.,Almo, S.C.,Schramm, V.L. (登録日: 2008-07-07, 公開日: 2009-03-10, 最終更新日: 2024-02-21)

• 主引用文献: Gutierrez, J.A.,Crowder, T.,Rinaldo-Matthis, A.,Ho, M.C.,Almo, S.C.,Schramm, V.L.; Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.; Nat.Chem.Biol., 5:251-257, 2009; PubMed: 19270684; DOI: 10.1038/nchembio.153

実験手法

X-RAY DIFFRACTION (2.3 Å)