3DMM

Crystal structure of the CD8 alpha beta/H-2Dd complex

3DMM の概要

• エントリーDOI: 10.2210/pdb3dmm/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, Synthetic peptide, ... (6 entities in total)
• 機能のキーワード: t cell co-receptor cd8ab mhc complex, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, secreted, envelope protein, alternative splicing, polymorphism, immune system
• 由来する生物種: Mus musculus; 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01900 P10300; Cell membrane ; Single-pass type I membrane protein : P01731
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 80119.84

構造登録者

Wang, R.,Natarajan, K.,Margulies, D.H. (登録日: 2008-07-01, 公開日: 2009-07-14, 最終更新日: 2023-08-30)

• 主引用文献: Wang, R.,Natarajan, K.,Margulies, D.H.; Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.; J.Immunol., 183:2554-2564, 2009; PubMed: 19625641; DOI: 10.4049/jimmunol.0901276

実験手法

X-RAY DIFFRACTION (2.6 Å)