3DLL

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

3DLL の概要

• エントリーDOI: 10.2210/pdb3dll/pdb
• 分子名称: rRNA-23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (33 entities in total)
• 機能のキーワード: ribosome, antibiotic, oxazolidinone, linezolid, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, methylation, metal-binding, zinc-finger
• 由来する生物種: Deinococcus radiodurans; 詳細
• タンパク質・核酸の鎖数: 30
• 化学式量合計: 1365757.44

構造登録者

Wilson, D.N.,Schluenzen, F.,Harms, J.M.,Starosta, A.L.,Connell, S.R.,Fucini, P. (登録日: 2008-06-27, 公開日: 2008-09-16, 最終更新日: 2023-11-01)

• 主引用文献: Wilson, D.N.,Schluenzen, F.,Harms, J.M.,Starosta, A.L.,Connell, S.R.,Fucini, P.; The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning; Proc.Natl.Acad.Sci.Usa, 105:13339-13344, 2008; PubMed: 18757750; DOI: 10.1073/pnas.0804276105

実験手法

X-RAY DIFFRACTION (3.5 Å)