3DL7

Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update

3DL7 の概要

• エントリーDOI: 10.2210/pdb3dl7/pdb
• 関連するPDBエントリー: 2c0p 2c0q 3DJY 3DKK 3DL4
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: hydrolase, tabun, organophosphate, aging, cell junction, glycoprotein, gpi-anchor, lipoprotein, membrane, neurotransmitter degradation, secreted, serine esterase, synapse
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121415.28

構造登録者

Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F. (登録日: 2008-06-26, 公開日: 2008-12-02, 最終更新日: 2021-03-31)

• 主引用文献: Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F.; Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.; J.Am.Chem.Soc., 130:16011-16020, 2008; PubMed: 18975951; DOI: 10.1021/ja804941z

実験手法

X-RAY DIFFRACTION (2.5 Å)