3DKK

Aged Form of Human Butyrylcholinesterase Inhibited by Tabun

3DKK の概要

• エントリーDOI: 10.2210/pdb3dkk/pdb
• 関連するPDBエントリー: 2C0P 2C0Q 3DJY 3DL4 3DL7
• 分子名称: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: hydrolase, tabun, organophosphate, aging, disease mutation, glycoprotein, serine esterase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62182.58

構造登録者

Nachon, F.,Carletti, E. (登録日: 2008-06-25, 公開日: 2008-12-02, 最終更新日: 2021-10-20)

• 主引用文献: Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F.; Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.; J.Am.Chem.Soc., 130:16011-16020, 2008; PubMed: 18975951; DOI: 10.1021/ja804941z

実験手法

X-RAY DIFFRACTION (2.31 Å)