3DHY
Crystal Structures of Mycobacterium tuberculosis S-Adenosyl-L-Homocysteine Hydrolase in Ternary Complex with Substrate and Inhibitors
3DHY の概要
エントリーDOI | 10.2210/pdb3dhy/pdb |
関連するPDBエントリー | 2ZIZ 2ZJ0 2ZJ1 3CE6 |
分子名称 | Adenosylhomocysteinase, 5'-S-ethyl-5'-thioadenosine, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
機能のキーワード | protein-substrate complex, dimer of dimers, nad binding domain, 37 amino acid insertion, solvent access channel, structural genomics, tuberculosis structural genomics consortium, tb structural genomics consortium, tbsgc, cytoplasm, hydrolase, nad, one-carbon metabolism, psi-2, protein structure initiative |
由来する生物種 | Mycobacterium tuberculosis |
細胞内の位置 | Cytoplasm (By similarity): P60176 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 221448.78 |
構造登録者 | Shetty, N.D.,Ioerger, T.R.,Gokulan, K.,Reddy, M.C.M.,Owen, J.L.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2008-06-19, 公開日: 2008-09-09, 最終更新日: 2023-08-30) |
主引用文献 | Reddy, M.C.,Kuppan, G.,Shetty, N.D.,Owen, J.L.,Ioerger, T.R.,Sacchettini, J.C. Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors. Protein Sci., 17:2134-2144, 2008 Cited by PubMed: 18815415DOI: 10.1110/ps.038125.108 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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