3DG7

Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone

3DG7 の概要

• エントリーDOI: 10.2210/pdb3dg7/pdb
• 関連するPDBエントリー: 3DG3 3DG6
• 分子名称: Muconate cycloisomerase, MAGNESIUM ION, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid, ... (4 entities in total)
• 機能のキーワード: muconate lactonizing enzyme, muconolactone binding, isomerase
• 由来する生物種: Mycobacterium smegmatis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 160743.78

構造登録者

Fedorov, A.A.,Fedorov, E.V.,Sakai, A.,Gerlt, J.A.,Almo, S.C. (登録日: 2008-06-12, 公開日: 2009-03-03, 最終更新日: 2024-03-20)

• 主引用文献: Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.; Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes; Biochemistry, 48:1445-1453, 2009; PubMed: 19220063; DOI: 10.1021/bi802277h

実験手法

X-RAY DIFFRACTION (2 Å)