3DEM

CUB1-EGF-CUB2 domain of HUMAN MASP-1/3

3DEM の概要

• エントリーDOI: 10.2210/pdb3dem/pdb
• 関連するPDBエントリー: 1nt0 1nzi
• 分子名称: Complement factor MASP-3, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: complement system, innate immunity, calcium binding sites, complement pathway, egf-like domain, glycoprotein, hydrolase, hydroxylation, immune response, protease, serine protease, sushi, lectin
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64466.34

構造登録者

Gaboriaud, C. (登録日: 2008-06-10, 公開日: 2008-07-01, 最終更新日: 2023-11-01)

• 主引用文献: Teillet, F.,Gaboriaud, C.,Lacroix, M.,Martin, L.,Arlaud, G.J.,Thielens, N.M.; Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins; J.Biol.Chem., 283:25715-25724, 2008; PubMed: 18596036; DOI: 10.1074/jbc.M803551200

実験手法

X-RAY DIFFRACTION (2.3 Å)