3DCG

Crystal Structure of the HIV Vif BC-box in Complex with Human ElonginB and ElonginC

3DCG の概要

• エントリーDOI: 10.2210/pdb3dcg/pdb
• 分子名称: Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, Virion infectivity factor, ... (4 entities in total)
• 機能のキーワード: hiv, vif, aids, host-virus interaction, membrane, phosphoprotein, rna-binding, ubl conjugation pathway, virion, nucleus, transcription, transcription regulation, ligase-viral protein complex, ligase/viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Host cytoplasm: Q15370; Nucleus (Probable): Q15369 P12504
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 57141.36

構造登録者

Stanley, B.J.,Ehrlich, E.S.,Short, L.,Yu, Y.,Xiao, Z.,Yu, X.-F.,Xiong, Y. (登録日: 2008-06-03, 公開日: 2008-07-08, 最終更新日: 2023-11-01)

• 主引用文献: Stanley, B.J.,Ehrlich, E.S.,Short, L.,Yu, Y.,Xiao, Z.,Yu, X.-F.,Xiong, Y.; Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly; J.Virol., 82:8656-8663, 2008; PubMed: 18562529; DOI: 10.1128/JVI.00767-08

実験手法

X-RAY DIFFRACTION (2.4 Å)