3DAX

Crystal structure of human CYP7A1

3DAX の概要

• エントリーDOI: 10.2210/pdb3dax/pdb
• 分子名称: Cytochrome P450 7A1, PROTOPORPHYRIN IX CONTAINING FE, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: cytochrome p450, cholesterol, cholesterol 7-alpha hydroxylase, structural genomics, structural genomics consortium, sgc, cholesterol metabolism, endoplasmic reticulum, heme, iron, lipid metabolism, membrane, metal-binding, microsome, monooxygenase, nadp, oxidoreductase, polymorphism, steroid metabolism
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114172.54

構造登録者

Strushkevich, N.V.,Tempel, W.,Dombrovski, L.,Dong, A.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Wilkstrom, M.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2008-05-30, 公開日: 2008-08-05, 最終更新日: 2023-08-30)

• 主引用文献: Strushkevich, N.V.,Tempel, W.,Dombrovski, L.,Dong, A.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Wilkstrom, M.,Bochkarev, A.,Park, H.; Crystal structure of human CYP7A1; To be Published,

実験手法

X-RAY DIFFRACTION (2.15 Å)