3D7C

Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2

3D7C の概要

• エントリーDOI: 10.2210/pdb3d7c/pdb
• 分子名称: General control of amino acid synthesis protein 5-like 2 (2 entities in total)
• 機能のキーワード: gcn5, bromodomain, amino-acid synthesis, structural genomics consortium, sgc, host-virus interaction, nucleus, phosphoprotein, transcription, transcription regulation, transferase, biosynthetic protein
• 由来する生物種: Homo sapiens
• 細胞内の位置: Nucleus: Q92830
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26574.63

構造登録者

Filippakopoulos, P.,Eswaran, J.,Picaud, S.,Fedorov, O.,Murray, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2008-05-21, 公開日: 2008-07-15, 最終更新日: 2023-08-30)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (2.06 Å)