3D6Y
Crystal structure of R275E mutant of BMRR bound to DNA and berberine
Summary for 3D6Y
Entry DOI | 10.2210/pdb3d6y/pdb |
Related | 1BOW 1EXJ 1R8E 2BOW 3D6Z 3D70 3D71 |
Descriptor | BMR promoter DNA, Multidrug-efflux transporter 1 regulator, BERBERINE, ... (5 entities in total) |
Functional Keywords | multidrug resistance, transcription regulation, protein-dna complex, activator, dna-binding, transcription regulator-dna complex, transcription regulator/dna |
Biological source | Bacillus subtilis More |
Total number of polymer chains | 2 |
Total formula weight | 41333.40 |
Authors | Newberry, K.J.,Brennan, R.G. (deposition date: 2008-05-20, release date: 2008-08-26, Last modification date: 2023-08-30) |
Primary citation | Newberry, K.J.,Huffman, J.L.,Miller, M.C.,Vazquez-Laslop, N.,Neyfakh, A.A.,Brennan, R.G. Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion J.Biol.Chem., 283:26795-26804, 2008 Cited by PubMed: 18658145DOI: 10.1074/jbc.M804191200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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