3D6N

Crystal Structure of Aquifex Dihydroorotase Activated by Aspartate Transcarbamoylase

3D6N の概要

• エントリーDOI: 10.2210/pdb3d6n/pdb
• 関連するPDBエントリー: 1xrf 1xrt
• 分子名称: Dihydroorotase, Aspartate carbamoyltransferase, ZINC ION, ... (5 entities in total)
• 機能のキーワード: reactor, chamber, pores, internal cavity, hydrolase, metal-binding, pyrimidine biosynthesis, transferase, hydrolase-transferase complex, hydrolase/transferase
• 由来する生物種: Aquifex aeolicus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80490.88

構造登録者

Edwards, B.F.P. (登録日: 2008-05-20, 公開日: 2009-01-20, 最終更新日: 2023-08-30)

• 主引用文献: Zhang, P.,Martin, P.D.,Purcarea, C.,Vaishnav, A.,Brunzelle, J.S.,Fernando, R.,Guy-Evans, H.I.,Evans, D.R.,Edwards, B.F.; Dihydroorotase from the hyperthermophile Aquifiex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis.; Biochemistry, 48:766-778, 2009; PubMed: 19128030; DOI: 10.1021/bi801831r

実験手法

X-RAY DIFFRACTION (2.3 Å)