3D5E

Crystal structure of human plasma platelet activating factor acetylhydrolase covalently inhibited by paraoxon

Summary for 3D5E

Entry DOI	10.2210/pdb3d5e/pdb
Related	3D59
Descriptor	Platelet-activating factor acetylhydrolase, DIETHYL PHOSPHONATE, FORMIC ACID, ... (4 entities in total)
Functional Keywords	plasma platelet-activating factor acetylhydrolase, secreted protein, alpha/beta-hydrolase-fold, ldl-bound; lipoprotein associated phospholipase a2, lp-pla2, group viia pla2, glycoprotein, hydrolase, lipid degradation, polymorphism, secreted, paraoxon
Biological source	Homo sapiens (Human)
Cellular location	Secreted, extracellular space: Q13093
Total number of polymer chains	2
Total formula weight	88001.34
Authors	Samanta, U.,Bahnson, B.J. (deposition date: 2008-05-16, release date: 2008-09-09, Last modification date: 2023-08-30)
Primary citation	Samanta, U.,Bahnson, B.J. Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase: STRUCTURAL IMPLICATION TO LIPOPROTEIN BINDING AND CATALYSIS. J.Biol.Chem., 283:31617-31624, 2008 Cited by PubMed: 18784071 DOI: 10.1074/jbc.M804750200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation