3D4V

Crystal Structure of an AlkA Host/Guest Complex N7MethylGuanine:Cytosine Base Pair

Summary for 3D4V

• Entry DOI: 10.2210/pdb3d4v/pdb
• Descriptor: DNA-3-methyladenine glycosylase 2, 5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(FMG)P*DTP*DGP*DCP*DC)-3', 5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3', ... (4 entities in total)
• Functional Keywords: alka, n7methylguanine, dna repair, host-guest complex, dna structure, dna damage, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 140418.59

Authors

Lee, S.,Bowman, B.R.,Wang, S.,Verdine, G.L. (deposition date: 2008-05-15, release date: 2008-09-09, Last modification date: 2024-02-21)

• Primary citation: Lee, S.,Bowman, B.R.,Ueno, Y.,Wang, S.,Verdine, G.L.; Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.; J.Am.Chem.Soc., 130:11570-11571, 2008; PubMed: 18686953; DOI: 10.1021/ja8025328

Experimental method

X-RAY DIFFRACTION (2.9 Å)