3D45

Crystal structure of mouse PARN in complex with m7GpppG

3D45 の概要

• エントリーDOI: 10.2210/pdb3d45/pdb
• 分子名称: Poly(A)-specific ribonuclease PARN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: parn, cap analogue, exonuclease, hydrolase, magnesium, metal-binding, nonsense-mediated mrna decay, nuclease, nucleus, phosphoprotein, rna-binding
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Nucleus: Q8VDG3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 118365.00

構造登録者

Wu, M.,Song, H. (登録日: 2008-05-13, 公開日: 2009-03-17, 最終更新日: 2023-08-30)

• 主引用文献: Wu, M.,Nilsson, P.,Henriksson, N.,Niedzwiecka, A.,Lim, M.K.,Cheng, Z.,Kokkoris, K.,Virtanen, A.,Song, H.; Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.; Structure, 17:276-286, 2009; PubMed: 19217398; DOI: 10.1016/j.str.2008.11.012

実験手法

X-RAY DIFFRACTION (3 Å)