3D2V

Structure of the eukaryotic TPP-specific riboswitch bound to the antibacterial compound pyrithiamine pyrophosphate

3D2V の概要

• エントリーDOI: 10.2210/pdb3d2v/pdb
• 関連するPDBエントリー: 2cky 3d2g 3D2X
• 分子名称: TPP-specific riboswitch, MAGNESIUM ION, 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM, ... (4 entities in total)
• 機能のキーワード: rna, riboswitch, antibiotic, thiamine pyrophosphate, pyrithiamine pyrophosphate, complex
• 由来する生物種: Arabidopsis thaliana
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50999.30

構造登録者

Thore, S.,Frick, C.,Ban, N. (登録日: 2008-05-09, 公開日: 2008-07-01, 最終更新日: 2023-08-30)

• 主引用文献: Thore, S.,Frick, C.,Ban, N.; Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch; J.Am.Chem.Soc., 130:8116-8117, 2008; PubMed: 18533652; DOI: 10.1021/ja801708e

実験手法

X-RAY DIFFRACTION (2 Å)