3D0I

Crystal structure of spike protein receptor-binding domain from the 2005-2006 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2

3D0I の概要

• エントリーDOI: 10.2210/pdb3d0i/pdb
• 関連するPDBエントリー: 2AJF 3D0G 3D0H
• 分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: sars coronavirus, spike protein, receptor-binding domain, rbd, angiotensin-converting enzyme 2, ace2, virus-host interface, host adaptation, cross-species infections, human, palm civet, carboxypeptidase, chloride, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, protease, secreted, transmembrane, envelope protein, host-virus interaction, lipoprotein, palmitate, virion, virulence
• 由来する生物種: Paguma larvata (Masked palm civet); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 180463.97

構造登録者

Li, F. (登録日: 2008-05-01, 公開日: 2008-07-08, 最終更新日: 2020-07-29)

• 主引用文献: Li, F.; Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections; J.Virol., 82:6984-6991, 2008; PubMed: 18448527; DOI: 10.1128/JVI.00442-08

実験手法

X-RAY DIFFRACTION (2.9 Å)