3CWU

Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxy-1,N6-ethenoadenine:Thymine Base Pair

Summary for 3CWU

• Entry DOI: 10.2210/pdb3cwu/pdb
• Related: 3CVS 3CVT 3CW7 3CWA 3CWS 3CWT
• Descriptor: DNA-3-methyladenine glycosylase 2, DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FE)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DTP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), ... (4 entities in total)
• Functional Keywords: alka, 2'-fluoro-2'-deoxy-1, n6-ethenoadenine, dna repair, host-guest complex, dna structure, dna damage, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 140434.58

Authors

Bowman, B.R.,Lee, S.,Wang, S.,Verdine, G.L. (deposition date: 2008-04-22, release date: 2008-09-02, Last modification date: 2024-02-21)

• Primary citation: Bowman, B.R.,Lee, S.,Wang, S.,Verdine, G.L.; Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.; Structure, 16:1166-1174, 2008; PubMed: 18682218; DOI: 10.1016/j.str.2008.04.012

Experimental method

X-RAY DIFFRACTION (2.8 Å)