Crystal Structure of the R132K:Y134F:R111L:T54V:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-trans-Retinoic Acid at 1.57 Angstroms Resolution

Summary for 3CWK

Related2fr3 2frs 2fs6 2g7b 2g78 2g79
DescriptorCellular retinoic acid-binding protein 2, SULFATE ION, RETINOIC ACID, ... (4 entities in total)
Functional Keywordscrabpii, retinoic acid, retinoids, beta barrel, high resolution, cytoplasm, nucleus, retinol-binding, transport, vitamin a, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P29373
Total number of polymer chains1
Total molecular weight15904.23
Vaezeslami, S.,Geiger, J.H. (deposition date: 2008-04-22, release date: 2008-09-09, Last modification date: 2017-10-25)
Primary citation
Vaezeslami, S.,Jia, X.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding.
Acta Crystallogr.,Sect.D, 64:1228-1239, 2008
PubMed: 19018099 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444908032216
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.174900.8%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution