3CU7

Human Complement Component 5

3CU7 の概要

• エントリーDOI: 10.2210/pdb3cu7/pdb
• 分子名称: Complement C5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: mg domain, complement, inflammation, anaphylatoxin, cleavage on pair of basic residues, complement alternate pathway, complement pathway, cytolysis, glycoprotein, immune response, inflammatory response, innate immunity, membrane attack complex, secreted, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 379355.17

構造登録者

Fredslund, F.,Andersen, G.R. (登録日: 2008-04-16, 公開日: 2008-06-10, 最終更新日: 2023-11-01)

• 主引用文献: Fredslund, F.,Laursen, N.S.,Roversi, P.,Jenner, L.,Oliveira, C.L.P.,Pedersen, J.S.,Nunn, M.A.,Lea, S.M.,Discipio, R.,Sottrup-Jensen, L.,Andersen, G.R.; Structure of and influence of a tick complement inhibitor on human complement component 5; Nat.Immunol., 9:753-760, 2008; PubMed: 18536718; DOI: 10.1038/ni.1625

実験手法

X-RAY DIFFRACTION (3.105 Å)