3CTT

Crystal complex of N-terminal Human Maltase-Glucoamylase with Casuarine

3CTT の概要

• エントリーDOI: 10.2210/pdb3ctt/pdb
• 関連するPDBエントリー: 2qly 2qmj
• 分子名称: Maltase-glucoamylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: glycosyl hydrolase family 31, alpha-glucosidase, glycoprotein, glycosidase, membrane, multifunctional enzyme, signal-anchor, sulfation, transmembrane, hydrolase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Apical cell membrane; Single-pass type II membrane protein: O43451
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 100158.52

構造登録者

Sim, L.,Rose, D.R. (登録日: 2008-04-14, 公開日: 2009-02-24, 最終更新日: 2023-08-30)

• 主引用文献: Cardona, F.,Parmeggiani, C.,Faggi, E.,Bonaccini, C.,Gratteri, P.,Sim, L.,Gloster, T.M.,Roberts, S.,Davies, G.J.,Rose, D.R.,Goti, A.; Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families; Chemistry, 15:1627-1636, 2009; PubMed: 19123216; DOI: 10.1002/chem.200801578

実験手法

X-RAY DIFFRACTION (2.1 Å)