Summary for 3CSJ
Entry DOI | 10.2210/pdb3csj/pdb |
Related | 3CSH 3CSI |
Descriptor | Glutathione S-transferase P, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | transferase, glutathione, detoxification, chlorambucil, polymorphism |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 47223.28 |
Authors | Parker, L.J. (deposition date: 2008-04-09, release date: 2008-07-01, Last modification date: 2023-08-30) |
Primary citation | Parker, L.J.,Ciccone, S.,Italiano, L.C.,Primavera, A.,Oakley, A.J.,Morton, C.J.,Hancock, N.C.,Bello, M.L.,Parker, M.W. The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380:131-144, 2008 Cited by PubMed: 18511072DOI: 10.1016/j.jmb.2008.04.066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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