3CPO

Crystal structure of ketosteroid isomerase D40N with bound 2-fluorophenol

Summary for 3CPO

Entry DOI	10.2210/pdb3cpo/pdb
Descriptor	Delta(5)-3-ketosteroid isomerase, 2-fluorophenol (3 entities in total)
Functional Keywords	enzyme, active site, hydrogen bond, geometry, isomerase, lipid metabolism, steroid metabolism
Biological source	Pseudomonas putida
Total number of polymer chains	1
Total formula weight	14659.62
Authors	Caaveiro, J.M.M.,Pybus, B.,Ringe, D.,Petsko, G. (deposition date: 2008-03-31, release date: 2008-09-23, Last modification date: 2023-08-30)
Primary citation	Sigala, P.A.,Kraut, D.A.,Caaveiro, J.M.M.,Pybus, B.,Ruben, E.A.,Ringe, D.,Petsko, G.A.,Herschlag, D. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole J.Am.Chem.Soc., 130:13696-13708, 2008 Cited by PubMed: 18808119 DOI: 10.1021/ja803928m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation