3CMZ

TEM-1 Class-A beta-lactamase L201P mutant apo structure

Summary for 3CMZ

• Entry DOI: 10.2210/pdb3cmz/pdb
• Related: 1JWP
• Descriptor: Beta-lactamase TEM, PHOSPHATE ION (3 entities in total)
• Functional Keywords: stabilization mutation, antibiotic resistance, hydrolase, plasmid, transposable element
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 29020.92

Authors

Marciano, D.C.,Wang, X.,Wang, J.,Chen, Y.,Thomas, V.L.,Shoichet, B.K.,Palzkill, T. (deposition date: 2008-03-24, release date: 2008-11-25, Last modification date: 2023-08-30)

• Primary citation: Marciano, D.C.,Pennington, J.M.,Wang, X.,Wang, J.,Chen, Y.,Thomas, V.L.,Shoichet, B.K.,Palzkill, T.; Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase; J.Mol.Biol., 384:151-164, 2008; PubMed: 18822298; DOI: 10.1016/j.jmb.2008.09.009

Experimental method

X-RAY DIFFRACTION (1.92 Å)