3CL3
Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome
Summary for 3CL3
Entry DOI | 10.2210/pdb3cl3/pdb |
Descriptor | ORF K13, NF-kappa-B essential modulator (2 entities in total) |
Functional Keywords | death effector domain, coiled-coil, coiled coil, cytoplasm, disease mutation, ectodermal dysplasia, host-virus interaction, nucleus, transcription, transcription regulation, viral protein-signaling protein complex, viral protein/signaling protein |
Biological source | Human gammaherpesvirus 8 More |
Total number of polymer chains | 4 |
Total formula weight | 70846.87 |
Authors | Bagneris, C.,Ageichik, A.V.,Cronin, N.,Boshoff, C.,Waksman, G.,Barrett, T. (deposition date: 2008-03-18, release date: 2008-06-17, Last modification date: 2024-02-21) |
Primary citation | Bagneris, C.,Ageichik, A.V.,Cronin, N.,Wallace, B.,Collins, M.,Boshoff, C.,Waksman, G.,Barrett, T. Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome. Mol.Cell, 30:620-631, 2008 Cited by PubMed: 18538660DOI: 10.1016/j.molcel.2008.04.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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