3CKD

Crystal structure of the C-terminal domain of the Shigella type III effector IpaH

3CKD の概要

• エントリーDOI: 10.2210/pdb3ckd/pdb
• 分子名称: Invasion plasmid antigen, secreted by the Mxi-Spa secretion machinery, SULFATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: e3 ubiquitin ligase, helical, type iii effector, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, ligase
• 由来する生物種: Shigella flexneri 2a str. 301
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 107498.46

構造登録者

Lam, R.,Singer, A.U.,Cuff, M.E.,Skarina, T.,Kagan, O.,DiLeo, R.,Edwards, A.M.,Joachimiak, A.,Savchenko, A.,Midwest Center for Structural Genomics (MCSG) (登録日: 2008-03-14, 公開日: 2008-03-25, 最終更新日: 2011-07-13)

• 主引用文献: Singer, A.U.,Rohde, J.R.,Lam, R.,Skarina, T.,Kagan, O.,Dileo, R.,Chirgadze, N.Y.,Cuff, M.E.,Joachimiak, A.,Tyers, M.,Sansonetti, P.J.,Parsot, C.,Savchenko, A.; Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.; Nat.Struct.Mol.Biol., 15:1293-1301, 2008; PubMed: 18997778; DOI: 10.1038/nsmb.1511

実験手法

X-RAY DIFFRACTION (2.65 Å)