3CGY

Crystal Structure of Salmonella Sensor Kinase PhoQ catalytic domain in complex with radicicol

3CGY の概要

• エントリーDOI: 10.2210/pdb3cgy/pdb
• 関連するPDBエントリー: 3CGZ
• 分子名称: Virulence sensor histidine kinase phoQ, RADICICOL (2 entities in total)
• 機能のキーワード: alpha-beta sandwich, bergerat fold, atp-binding, growth regulation, inner membrane, kinase, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, transferase, transmembrane, two-component regulatory system, virulence
• 由来する生物種: Salmonella typhimurium
• 細胞内の位置: Cell inner membrane; Multi-pass membrane protein (By similarity): P14147
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53182.04

構造登録者

Guarnieri, M.T.,Zhang, L.,Shen, J.,Zhao, R. (登録日: 2008-03-06, 公開日: 2008-05-13, 最終更新日: 2023-08-30)

• 主引用文献: Guarnieri, M.T.,Zhang, L.,Shen, J.,Zhao, R.; The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ.; J.Mol.Biol., 379:82-93, 2008; PubMed: 18440021; DOI: 10.1016/j.jmb.2008.03.036

実験手法

X-RAY DIFFRACTION (2.6 Å)