3CBH

THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI

3CBH の概要

• エントリーDOI: 10.2210/pdb3cbh/pdb
• 分子名称: CELLOBIOHYDROLASE II CORE PROTEIN (1 entity in total)
• 機能のキーワード: hydrolase (o-glycosyl)
• 由来する生物種: Hypocrea jecorina
• 細胞内の位置: Secreted: P07987
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39055.30

構造登録者

Jones, T.A.,Rouvinen, J. (登録日: 1990-08-06, 公開日: 1991-01-15, 最終更新日: 2024-02-21)

主引用文献

Rouvinen, J.,Bergfors, T.,Teeri, T.,Knowles, J.K.,Jones, T.A.
Three-dimensional structure of cellobiohydrolase II from Trichoderma reesei.
Science, 249:380-386, 1990

PubMed Abstract: The enzymatic degradation of cellulose is an important process, both ecologically and commercially. The three-dimensional structure of a cellulase, the enzymatic core of CBHII from the fungus Trichoderma reesei reveals an alpha-beta protein with a fold similar to but different from the widely occurring barrel topology first observed in triose phosphate isomerase. The active site of CBHII is located at the carboxyl-terminal end of a parallel beta barrel, in an enclosed tunnel through which the cellulose threads. Two aspartic acid residues, located in the center of the tunnel are the probable catalytic residues.

PubMed: 2377893

実験手法

X-RAY DIFFRACTION (2 Å)