3CAM

Crystal structure of the cold shock domain protein from Neisseria meningitidis

3CAM の概要

• エントリーDOI: 10.2210/pdb3cam/pdb
• 分子名称: Cold-shock domain family protein (2 entities in total)
• 機能のキーワード: neisseria meningitidis, cold shock protein, chain swap, structural genomics, oxford protein production facility, oppf, gene regulation
• 由来する生物種: Neisseria meningitidis MC58
• 細胞内の位置: Cytoplasm : Q9JZZ4
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14593.75

構造登録者

Ren, J.,Sainsbury, S.,Owens, R.J.,Oxford Protein Production Facility (OPPF) (登録日: 2008-02-20, 公開日: 2008-03-25, 最終更新日: 2024-11-20)

主引用文献

Ren, J.,Nettleship, J.E.,Sainsbury, S.,Saunders, N.J.,Owens, R.J.
Structure of the cold-shock domain protein from Neisseria meningitidis reveals a strand-exchanged dimer.
Acta Crystallogr.,Sect.F, 64:247-251, 2008

PubMed Abstract: The structure of the cold-shock domain protein from Neisseria meningitidis has been solved to 2.6 A resolution and shown to comprise a dimer formed by the exchange of two beta-strands between protein monomers. The overall fold of the monomer closely resembles those of other bacterial cold-shock proteins. The neisserial protein behaved as a monomer in solution and was shown to bind to a hexathymidine oligonucleotide with a stoichiometry of 1:1 and a K(d) of 1.25 microM.

PubMed: 18391418
DOI: 10.1107/S1744309108005411

実験手法

X-RAY DIFFRACTION (2.6 Å)