3C7R

Crystal Structure of HIV-1 subtype F DIS extended duplex RNA bound to neomycin

Summary for 3C7R

Related2QEK 3C44 3C3Z 3C5D
DescriptorHIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION, ... (4 entities in total)
Functional Keywordshiv-1, rna, aminoglycoside, neomycin, extended duplex
Total number of polymer chains2
Total molecular weight16234.4
Authors
Freisz, S.,Lang, K.,Micura, R.,Dumas, P.,Ennifar, E. (deposition date: 2008-02-08, release date: 2008-05-06, Last modification date: 2011-07-13)
Primary citation
Freisz, S.,Lang, K.,Micura, R.,Dumas, P.,Ennifar, E.
Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47:4110-4113, 2008
PubMed: 18435520 (PDB entries with the same primary citation)
DOI: 10.1002/anie.200800726
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRSRZ outliers0.279140MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3c7r
no rotation
Molmil generated image of 3c7r
rotated about x axis by 90°
Molmil generated image of 3c7r
rotated about y axis by 90°