3C6B
Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant
Summary for 3C6B
| Entry DOI | 10.2210/pdb3c6b/pdb |
| Related | 1pv1 |
| Descriptor | S-formylglutathione hydrolase (2 entities in total) |
| Functional Keywords | cysteine sulfenic acid, serine hydrolase, thioesterase, formaldehyde, organophosphate, cytoplasm, serine esterase, hydrolase |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) |
| Cellular location | Cytoplasm : P40363 |
| Total number of polymer chains | 1 |
| Total formula weight | 34056.18 |
| Authors | Legler, P.M.,Millard, C.B. (deposition date: 2008-02-04, release date: 2008-08-12, Last modification date: 2023-11-15) |
| Primary citation | Legler, P.M.,Kumaran, D.,Swaminathan, S.,Studier, F.W.,Millard, C.B. Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase. Biochemistry, 47:9592-9601, 2008 Cited by PubMed: 18707125DOI: 10.1021/bi8010016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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