3C4M
Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)
3C4M の概要
エントリーDOI | 10.2210/pdb3c4m/pdb |
関連するBIRD辞書のPRD_ID | PRD_900001 |
分子名称 | Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total) |
機能のキーワード | parathyroid hormone, g-protein-coupled receptor, sugar transport, transport, cleavage on pair of basic residues, disease mutation, secreted, dwarfism, glycoprotein, membrane, receptor, transducer, transmembrane, membrane protein |
由来する生物種 | Escherichia coli (, human) 詳細 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 126372.39 |
構造登録者 | |
主引用文献 | Pioszak, A.A.,Xu, H.E. Molecular recognition of parathyroid hormone by its G protein-coupled receptor. Proc.Natl.Acad.Sci.Usa, 105:5034-5039, 2008 Cited by PubMed: 18375760DOI: 10.1073/pnas.0801027105 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.95 Å) |
構造検証レポート
検証レポート(詳細版)
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