3C4M

Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)

3C4M の概要

• エントリーDOI: 10.2210/pdb3c4m/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: parathyroid hormone, g-protein-coupled receptor, sugar transport, transport, cleavage on pair of basic residues, disease mutation, secreted, dwarfism, glycoprotein, membrane, receptor, transducer, transmembrane, membrane protein
• 由来する生物種: Escherichia coli (, human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 126372.39

構造登録者

Pioszak, A.A.,Xu, H.E. (登録日: 2008-01-30, 公開日: 2008-04-08, 最終更新日: 2023-08-30)

• 主引用文献: Pioszak, A.A.,Xu, H.E.; Molecular recognition of parathyroid hormone by its G protein-coupled receptor.; Proc.Natl.Acad.Sci.Usa, 105:5034-5039, 2008; PubMed: 18375760; DOI: 10.1073/pnas.0801027105

実験手法

X-RAY DIFFRACTION (1.95 Å)