3BXX

Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site

Summary for 3BXX

Entry DOI	10.2210/pdb3bxx/pdb
Related	2IOD 3C1T
Descriptor	dihydroflavonol 4-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ... (4 entities in total)
Functional Keywords	rossmann fold, oxidoreductase
Biological source	Vitis vinifera (wine grape)
Total number of polymer chains	6
Total formula weight	233346.62
Authors	Trabelsi, N.,Petit, P.,Granier, T.,Langlois d'Estaintot, B.,Delrot, S.,Gallois, B. (deposition date: 2008-01-15, release date: 2008-10-21, Last modification date: 2024-02-21)
Primary citation	Trabelsi, N.,Petit, P.,Manigand, C.,Langlois d'Estaintot, B.,Granier, T.,Chaudiere, J.,Gallois, B. Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols Acta Crystallogr.,Sect.D, D64:883-891, 2008 Cited by PubMed: 18645237 DOI: 10.1107/S0907444908017769 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation