3BWF
Crystal structure of the human Pim1 in complex with an osmium compound
Summary for 3BWF
Entry DOI | 10.2210/pdb3bwf/pdb |
Descriptor | Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION, PYRIDOCARBAZOLE CYCLOPENTADIENYL OS(CO) COMPLEX, ... (4 entities in total) |
Functional Keywords | transferase, pim1, kinase, atp-binding, phosphorylation, alternative initiation, cytoplasm, manganese, membrane, metal-binding, nucleotide-binding, nucleus, phosphoprotein, proto-oncogene, serine/threonine-protein kinase |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 36310.23 |
Authors | Maksimoska, J.,Filippakopoulos, P.,Knapp, S.,Meggers, E. (deposition date: 2008-01-09, release date: 2008-06-24, Last modification date: 2024-02-21) |
Primary citation | Maksimoska, J.,Williams, D.S.,Atilla-Gokcumen, G.E.,Smalley, K.S.,Carroll, P.J.,Webster, R.D.,Filippakopoulos, P.,Knapp, S.,Herlyn, M.,Meggers, E. Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry, 14:4816-4822, 2008 Cited by PubMed: 18425743DOI: 10.1002/chem.200800294 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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