3BWF

Crystal structure of the human Pim1 in complex with an osmium compound

3BWF の概要

• エントリーDOI: 10.2210/pdb3bwf/pdb
• 分子名称: Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION, PYRIDOCARBAZOLE CYCLOPENTADIENYL OS(CO) COMPLEX, ... (4 entities in total)
• 機能のキーワード: transferase, pim1, kinase, atp-binding, phosphorylation, alternative initiation, cytoplasm, manganese, membrane, metal-binding, nucleotide-binding, nucleus, phosphoprotein, proto-oncogene, serine/threonine-protein kinase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36310.23

構造登録者

Maksimoska, J.,Filippakopoulos, P.,Knapp, S.,Meggers, E. (登録日: 2008-01-09, 公開日: 2008-06-24, 最終更新日: 2024-02-21)

• 主引用文献: Maksimoska, J.,Williams, D.S.,Atilla-Gokcumen, G.E.,Smalley, K.S.,Carroll, P.J.,Webster, R.D.,Filippakopoulos, P.,Knapp, S.,Herlyn, M.,Meggers, E.; Similar biological activities of two isostructural ruthenium and osmium complexes.; Chemistry, 14:4816-4822, 2008; PubMed: 18425743; DOI: 10.1002/chem.200800294

実験手法

X-RAY DIFFRACTION (2.35 Å)