3BUA

Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex

Summary for 3BUA

Related3BU8 3BQO
DescriptorTelomeric repeat-binding factor 2, DNA cross-link repair 1B protein (3 entities in total)
Functional Keywordstrf2 trfh domain dimerization domain apollo peptide, alternative splicing, cell cycle, chromosomal protein, dna-binding, nucleus, phosphoprotein, telomere, dna damage, dna repair, polymorphism, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q15554
Chromosome, telomere Q9H816
Total number of polymer chains8
Total molecular weight112226.21
Authors
Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. (deposition date: 2008-01-02, release date: 2008-02-19, Last modification date: 2011-07-13)
Primary citation
Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M.
A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319:1092-1096, 2008
PubMed: 18202258 (PDB entries with the same primary citation)
DOI: 10.1126/science.1151804
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.252263.3%13.7%8.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload