3BTR

AR-NLS:Importin-alpha complex

3BTR の概要

• エントリーDOI: 10.2210/pdb3btr/pdb
• 分子名称: Importin subunit alpha-2, Androgen receptor (3 entities in total)
• 機能のキーワード: importin-alpha-androgen receptor complex, cytoplasm, nucleus, phosphoprotein, protein transport, transport, disease mutation, dna-binding, lipid-binding, metal-binding, polymorphism, steroid-binding, transcription, transcription regulation, triplet repeat expansion, ubl conjugation, zinc, zinc-finger, hormone
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P52293; Nucleus: P10275
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47875.92

構造登録者

Cutress, M.L.,Whitaker, H.C.,Mills, I.G.,Stewart, M.,Neal, D.E. (登録日: 2007-12-30, 公開日: 2008-12-30, 最終更新日: 2023-11-01)

• 主引用文献: Cutress, M.L.,Whitaker, H.C.,Mills, I.G.,Stewart, M.,Neal, D.E.; Structural basis for the nuclear import of the human androgen receptor; J.Cell.Sci., 121:957-968, 2008; PubMed: 18319300; DOI: 10.1242/jcs.022103

実験手法

X-RAY DIFFRACTION (2.6 Å)