3BRT

NEMO/IKK association domain structure

3BRT の概要

• エントリーDOI: 10.2210/pdb3brt/pdb
• 関連するPDBエントリー: 3BRV
• 分子名称: Inhibitor of nuclear factor kappa-B kinase subunit beta,Inhibitor of nuclear factor kappa-B kinase subunit alpha, NF-kappa-B essential modulator (3 entities in total)
• 機能のキーワード: nemo, ikk-gamma, fip3, ikkap1, nf-kb essential modulator, acetylation, atp-binding, cytoplasm, kinase, nucleotide-binding, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase, coiled coil, disease mutation, ectodermal dysplasia, host-virus interaction, nucleus, transcription, transcription regulation, transferase-transcription complex, transferase/transcription
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm : O15111 Q9Y6K9
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 27136.65

構造登録者

Silvian, L.F. (登録日: 2007-12-21, 公開日: 2008-04-22, 最終更新日: 2024-02-21)

• 主引用文献: Rushe, M.,Silvian, L.,Bixler, S.,Chen, L.L.,Cheung, A.,Bowes, S.,Cuervo, H.,Berkowitz, S.,Zheng, T.,Guckian, K.,Pellegrini, M.,Lugovskoy, A.; Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site.; Structure, 16:798-808, 2008; PubMed: 18462684; DOI: 10.1016/j.str.2008.02.012

実験手法

X-RAY DIFFRACTION (2.25 Å)