3BRB
Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with ADP
Summary for 3BRB
Entry DOI | 10.2210/pdb3brb/pdb |
Related | 2P0C 3BPR |
Descriptor | Proto-oncogene tyrosine-protein kinase MER, CHLORIDE ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | atp-binding, disease mutation, glycoprotein, kinase, nucleotide-binding, phosphorylation, proto-oncogene, receptor, retinitis pigmentosa, sensory transduction, transferase, tyrosine-protein kinase, vision, structural genomics, structural genomics consortium, sgc, immunoglobulin domain, membrane, phosphoprotein, transmembrane |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein (By similarity): Q12866 |
Total number of polymer chains | 2 |
Total formula weight | 72951.24 |
Authors | Walker, J.R.,Huang, X.,Finerty Jr, P.J.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-12-21, release date: 2008-01-22, Last modification date: 2023-08-30) |
Primary citation | Huang, X.,Finerty, P.,Walker, J.R.,Butler-Cole, C.,Vedadi, M.,Schapira, M.,Parker, S.A.,Turk, B.E.,Thompson, D.A.,Dhe-Paganon, S. Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165:88-96, 2009 Cited by PubMed: 19028587DOI: 10.1016/j.jsb.2008.10.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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