3BPL

Crystal structure of the IL4-IL4R-Common Gamma ternary complex

3BPL の概要

• エントリーDOI: 10.2210/pdb3bpl/pdb
• 関連するPDBエントリー: 3BPN 3BPO
• 分子名称: Interleukin-4, Interleukin-4 receptor alpha chain, Cytokine receptor common gamma chain, ... (7 entities in total)
• 機能のキーワード: il4, il13, receptor, cytokine, b-cell activation, glycoprotein, growth factor, secreted, immune response, membrane, phosphoprotein, transmembrane, disease mutation, host-virus interaction, scid, cytokine-receptor complex, cytokine-cytokine receptor complex, cytokine/cytokine receptor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 64030.83

構造登録者

Garcia, K.C. (登録日: 2007-12-18, 公開日: 2008-02-05, 最終更新日: 2021-10-20)

• 主引用文献: Laporte, S.L.,Juo, Z.S.,Vaclavikova, J.,Colf, L.A.,Qi, X.,Heller, N.M.,Keegan, A.D.,Garcia, K.C.; Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.; Cell(Cambridge,Mass.), 132:259-272, 2008; PubMed: 18243101; DOI: 10.1016/j.cell.2007.12.030

実験手法

X-RAY DIFFRACTION (2.93 Å)