3BO8
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
3BO8 の概要
エントリーDOI | 10.2210/pdb3bo8/pdb |
関連するPDBエントリー | 1W72 |
分子名称 | HLA class I histocompatibility antigen, A-1 alpha chain, Beta-2-microglobulin, nonameric peptide from Melanoma-associated antigen 1, ... (5 entities in total) |
機能のキーワード | melanoma associated antigen, mage, mage-a1, major histocompatibility complex, mhc, human leukocyte antigen, hla, hla-a1, hla-a010101, tcr, t-cell receptor, antibody, fab-hyb3, hyb3, glycoprotein, host-virus interaction, immune response, immunoglobulin domain, membrane, mhc i, sulfation, transmembrane, disease mutation, glycation, pyrrolidone carboxylic acid, secreted, tumor antigen, immune system |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Membrane; Single-pass type I membrane protein: P30443 Secreted: P61769 Cytoplasm: P43355 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 44769.56 |
構造登録者 | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B. (登録日: 2007-12-17, 公開日: 2008-12-23, 最終更新日: 2023-11-01) |
主引用文献 | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B. Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity Protein Sci., 18:37-49, 2009 Cited by PubMed: 19177349DOI: 10.1002/pro.4 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.8 Å) |
構造検証レポート
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