3BLX

Yeast Isocitrate Dehydrogenase (Apo Form)

Summary for 3BLX

Related3BLV 3BLW
DescriptorIsocitrate dehydrogenase [NAD] subunit 1, Isocitrate dehydrogenase [NAD] subunit 2 (2 entities in total)
Functional Keywordstca cycle, oxidative metabolism, allostery, dehydrogenase, decarboxylase, allosteric enzyme, magnesium, manganese, metal-binding, mitochondrion, nad, oxidoreductase, rna-binding, transit peptide, tricarboxylic acid cycle, phosphoprotein
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationMitochondrion P28834
Mitochondrion matrix P28241
Total number of polymer chains16
Total molecular weight607323.03
Authors
Taylor, A.B.,Hu, G.,Hart, P.J.,McAlister-Henn, L. (deposition date: 2007-12-11, release date: 2008-02-05, Last modification date: 2011-07-13)
Primary citation
Taylor, A.B.,Hu, G.,Hart, P.J.,McAlister-Henn, L.
Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283:10872-10880, 2008
PubMed: 18256028 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M708719200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258201.9%10.0%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution