3BLO

TGT mutant in complex with queuine

3BLO の概要

• エントリーDOI: 10.2210/pdb3blo/pdb
• 関連するPDBエントリー: 2nqz 2nso 3bll
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ... (5 entities in total)
• 機能のキーワード: tgt mutant, queuine, glycosyltransferase, metal-binding, queuosine biosynthesis, transferase, trna processing
• 由来する生物種: Zymomonas mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43314.39

構造登録者

Tidten, N.,Heine, A.,Reuter, K.,Klebe, G. (登録日: 2007-12-11, 公開日: 2008-12-16, 最終更新日: 2023-11-01)

• 主引用文献: Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K.; Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor; Plos One, 8:e64240-e64240, 2013; PubMed: 23704982; DOI: 10.1371/journal.pone.0064240

実験手法

X-RAY DIFFRACTION (1.6 Å)